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Biochemistry of Cell Damage and Protection - (7th Semester)

[ 4th Year ]
LECTURER: Nikolaos Balatsos
CONTENT - Aim of the course

The aim of the course is to introduce the students to the main effects of several sources of damage at the cellular and the molecuar level. A conceptual framework is provided in order to present many levels of damage, such as radiation or temperature, but also their advantages to the organism. Another aim of the course is to emphasize to the biochemistry of the developed strategies and mechanisms to repair the damages and protect the organism.

ANALYTICAL DESCRIPTION OF THE COURSE
  • INTRODUCTION – SOURCES OF DAMAGE
  • TISSUE AND CELL WOUND HEALING
  • MOLECULAR MECHANISMS OF WOUND REPAIR
  • RADIATION: DAMAGE AND ADVANTAGES
  • CIRCADIAN RHYTHMS AND TEMPERATURE
  • OXIDATIVE STRESS
  • METALS AND DAMAGE
  • DNA REPAIR AND APOPTOSIS
ASSESSMENT

The performace of the students is evaluated from successful completion of personal assignment.

READING SUGGESTIONS
  • Molnar J.A., “Nutrition and Wound Healing” Taylor & Francis, 2007.
  • Caldecott K.W., “Eukaryotic DNA Damage Surveillance and Repair”, Landes Biosciences/Eurekah.com and Kluwer Academic/Plenum Publisers, 2004.
 TEACHING MATERIAL / E-class

 http://eclass.uth.gr/eclass/SEYC128/

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