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Bioinformatics (4th Semester)

[ 2nd  Year]
Lecturer: Grigorios Amoutzias
Content - Aim of the course

This course is offered to the students of the Department of Biochemistry and Biotechnology in the 4th semester. During the two hours/week lectures and the 3 two-hour practical courses the students are familiarized with the most important biological databases, with the principles, algorithms and implementation of Sequence Analysis, Phylogenetics, Genomics and Functional Genomics.

Αnalytical Description of the course
  • Biological Databases
  • Dotplots
  • Pairwise alignment
  • Homology Search – Blast/PSI-BLAST
  • Multiple Sequence analysis/Motifs/Profiles/HMMs
  • Principles of Phylogenetics
  • Phylogenetic algorithms
  • Phylogeny and implementations
  • Genomics – Next Generation sequencing technologies, data analysis and implementations
  • Functional Genomics - technologies, data analysis and implementations
Practicals
  • Biological Databases
  • Homology Search – Blast/PSI-BLAST
  • Multiple Sequence analysis and Phylogenetics with the Seaview software

Practicals are mandatory and must be successfully completed for the students to be allowed to take part in the final examination.

Assessment

The students are evaluated according to their performance in the written examination at the end of the semester.

Reading Suggestions
  • Andreas D. Baxevanis & B.F. Francis Quellette.
  • Σοφία Κοσσίδα. Βιοπληροφορική - Δυνατότητες & Προοπτικές.
  • Jin Xiong. Essential Bioinformatics.
  • David W. Mount. Bioinformatics. Sequence and genome analysis.

 

 Teaching Material / E-class 

http://eclass.uth.gr/eclass/modules/document/?course=SEYC134

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